New studies say that diabetes patients have the potential to synthesize
their own insulin, now offering hope to the millions around the world suffering
from diabetes and leading to the development of a therapy that would enable
diabetics to produce and retain their own insulin for a longer time period.
This can minimize the risk of complications in diabetics as well as
significantly reduce the need for pharmaceutical interventions.
Type 1 Diabetics Can Renew their Capacity to Synthesize Insulin
Type 1 Diabetics Can Renew their Capacity to Synthesize Insulin
A study conducted by the researchers at the Peninsula Medical School
revealed that the insulin secreting ²-cells can proliferate in type 1 diabetics
who have been recently diagnosed with the disease. Degeneration of the ²-cells
present in the pancreas is the major cause of type 1 diabetes.
The researchers collected specimens of pancreas from type1 diabetes patients who died soon after the diagnosis of the disease. They used the specimens to understand the cellular process that takes place in the ²-cells of the individuals with type1 diabetes. The researchers found that the body responded to the ongoing process of destruction by inducing proliferation of islet cells. The researchers concluded that type 1 diabetes patients who were recently diagnosed with disease experienced a 10 fold increase in islet cell regeneration.
We are still unsure what triggers the islet cell replication in type1 diabetes. However, we are beginning to leard of the involvement of an immune mediator.
Previously, it was thought that ²-cells do not readily replicate once a patient develops type1 diabetes. New research findings suggest that in the future it might be possible for a newly diagnosed type 1 diabetic to regain the ability to replace the destroyed ²-cells with new ones and restore his body’s ability to produce insulin.
The researchers collected specimens of pancreas from type1 diabetes patients who died soon after the diagnosis of the disease. They used the specimens to understand the cellular process that takes place in the ²-cells of the individuals with type1 diabetes. The researchers found that the body responded to the ongoing process of destruction by inducing proliferation of islet cells. The researchers concluded that type 1 diabetes patients who were recently diagnosed with disease experienced a 10 fold increase in islet cell regeneration.
We are still unsure what triggers the islet cell replication in type1 diabetes. However, we are beginning to leard of the involvement of an immune mediator.
Previously, it was thought that ²-cells do not readily replicate once a patient develops type1 diabetes. New research findings suggest that in the future it might be possible for a newly diagnosed type 1 diabetic to regain the ability to replace the destroyed ²-cells with new ones and restore his body’s ability to produce insulin.
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